
The use of HT29 clonal cell lines to examine the role of VEGF on …
May 1, 2005 · In the present study, clonal cell lines of a single tumor type, a human colon carcinoma (HT29), were generated via infection with a recombinant adeno-associated virus to …
Diallyl trisulfide inhibits migration, invasion and angiogenesis of ...
In HT29 cells, DATS inhibited migration and invasion through the inhibition of focal adhesion kinase (FAK), extracellular signal-regulated kinase, c-Jun N-terminal kinase and p38 which …
[Construction of adenovirus expressing anti-vascular ... - PubMed
This study was to construct replication deficient adenovirus carrying anti-VEGF hairpin ribozyme and investigate its inhibitory effects on VEGF expression and growth of colorectal cancer HT …
Expression and function of vascular endothelial growth factor …
Feb 21, 2005 · To identify the signaling pathways activated by VEGFR-1, we treated HT-29 cells with VEGF-A or-B for various periods and analysed signaling intermediates by Western blotting.
Acquired tumor cell resistance to sunitinib causes resistance in a HT ...
We compared growth properties of in vitro sunitinib resistant HT-29 colon cancer cells with the parental HT-29 cells in a murine model and determined their in vivo sensitivity to sunitinib …
NO-donating aspirin inhibits angiogenesis by suppressing VEGF ...
Jun 9, 2008 · In the present study, we used HT-29 xenografts in nude mice to explore whether NO-ASA inhibits tumor-associated angiogenesis. Our findings document a significant …
Effects of meloxicam on vascular endothelial growth factor and ...
The mRNA expressions of VEGF and Ang-2 in cultured HT-29 were determined by real-time quantitative reverse-transcription polymerase chain reaction. Our results showed that …
Effect of down-regulating VEGF on proliferation of colon
We designed specific small interfering RNA (siRNA) targeting vascular endothelial growth factor (VEGF) mRNA and synthesized oligo fragments, then siRNA was obtained by in vitro …
Effect of down-regulating VEGF on proliferation of colon
Two groups of siRNA targeting human VEGF effectively inhibited proliferation of HT-29 cells after transfection. The secretion of VEGF protein also notably decreased, but the control scramble …
Gene Therapy-Based Intracellular Cytotoxicity Using the Shigatoxin 1A1 Gene. of E1 is controlled by the human VEGF promoter, AdVEGFE1. This virus achieved good levels of viral replication …
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