
Targeting tumor-associated macrophages in hepatocellular …
Feb 15, 2023 · As one of the main members of the tumor microenvironment (TME) of HCC, tumor-associated macrophages (TAMs) play a critical role in its occurrence and development, …
Tumor-Associated Macrophages in Hepatocellular Carcinoma …
Tumor-associated macrophages (TAMs) actively participate in tumor-related inflammation, representing the main type of inflammatory cells in the tumor microenvironment, setting the …
Role of tumor-associated macrophages in hepatocellular …
Aug 24, 2024 · Evidence has shown that TAMs play a crucial role in HCC, through its interaction with other immune cells in the TME. This review summarizes the origin and phenotypic …
Individualized precision treatment: Targeting TAM in HCC
Aug 28, 2019 · This article reviews studies on the role of TAM to affect HCC treatment and provides insight into the potential individualized precision monotherapy or combination therapy …
The role of tumor‐associated macrophages in hepatocellular …
TAMs can produce cytokines, induce EMT in HCC cells, and enhance CSC characteristics, thus improving the ability of invasion and metastasis. In the margins of human HCC, there is a …
Tumor‑associated macrophages activated in the tumor …
Sep 6, 2024 · The TAM polarization in HCC tumors is M2. Both direct and indirect methods for TAMs to regulate the development of HCC are discussed. TAMs indirectly support HCC …
Biological impact and therapeutic implication of tumor-associated ...
Jul 12, 2024 · Tumor-associated macrophages (TAMs) play a significant role in the tumor microenvironment of hepatocellular carcinoma (HCC), with a predominant M2 polarization …
Targeting tumor-associated macrophages in hepatocellular …
As one of the main members of the tumor microenvironment (TME) of HCC, tumor-associated macrophages (TAMs) play a critical role in its occurrence and development, including …
Targeting tumor associated macrophages in hepatocellular …
May 1, 2022 · Current targeting TAMs to treat HCC have been achieved a promising therapeutic outcome by eliminating TAMs present, blocking recruitment of TAMs, reprogramming TAMs …
The role of tumor-associated macrophages in primary …
Tumor-associated macrophages (TAMs) inhepatocellularcarcinoma (HCC) play a prominent role in tumormicroenvironment by presenting M1 (induced by IFN γ along with LPS) and M2 …