Symptoms of CNS-GVHD are diverse and non-specific, including convulsions, consciousness-related symptoms, motor and sensory symptoms, dysarthria, aphasia, weakness, and paralysis.

Central nervous system (CNS) involvement of graft versus host disease (GvHD) is a rare cause of CNS disorders after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Chronic CNS GvHD symptoms are heterogeneous and include ...

Mar 3, 2022 · In this issue of Blood, Adams et al 1 present a novel mouse model of central nervous system (CNS) chronic graft-versus-host disease (GVHD) and identify unique mediators of this understudied complication after allogeneic hematopoietic stem cell transplantation (HSCT).

Central nervous system graft-versus-host disease can present quite a diagnostic challenge. We herein present a case of histologically-confirmed chronic graft versus host disease (GVHD) involving the central nervous system that occurred at …

Oct 23, 2024 · This study supports that immune-mediated CNS manifestations may occur following allo-HSCT. These can be associated with both acute and chronic GvHD and carry a grim prognosis. The clinical presentation as well as the radiological and …

Oct 23, 2024 · In this multicentre retrospective study, we analysed the clinical, biological, radiological and histopathological characteristics, as well as the clinical course of 66 patients diagnosed with possible CNS-GvHD (pCNS-GvHD), selected by predetermined diagnostic criteria.

CNS-related GvHD is a rare cause of CNS disorders after allo-HSCT and is associated with a poor prognosis.

CNS-related GvHD is a rare cause of CNS disorders after Allo-HSCT and is associated with a poor prognosis. The diagnosis of CNS-GvHD by the 2010 consensus criteria is based on rigid criteria and does not cover a majority of cases with strong clinical suspicion.

Aug 5, 2024 · Rarely, chronic graft-versus-host disease (cGVHD) can manifest with unusual—or “atypical”—complications, including within the central nervous system (CNS). Oncology nurses caring for patients with acute or cGVHD need to understand CNS involvement to empower patients and caregivers for early recognition and reporting. What Is Atypical cGVHD?

Graft-versus-host disease (GVHD) is a serious complication of allogeneic stem cell transplantation (SCT). Here, we report a rare case of GVHD involving the central nervous system (CNS).