The term G4 DNA was originally reserved for these tetramolecular structures that might play a role in meiosis. [5] However, as currently used in molecular biology, the term G4 can mean G …

Apr 20, 2020 · Experiments using chemical, molecular and cell biology methods have demonstrated that G4s exist in chromatin DNA and in RNA, and have linked G4 formation with …

Endogenous DNA G-quadruplex (G4) structures have been detected in human cells and mapped in genomic DNA and in an endogenous chromatin context by adapting next-generation …

Aug 30, 2021 · G-quadruplex (G4) DNA is a type of quadruple helix structure formed by a continuous guanine-rich DNA sequence. Emerging evidence in recent years authenticated that …

We propose that G4 motifs and structures that participate in key processes compose the G4 genome, analogous to the transcriptome, proteome, or metabolome. This is a new view of the …

Feb 22, 2017 · Single-stranded guanine-rich DNA sequences can fold into stable intramolecular and intermolecular four-stranded non-B DNA structures called G-quadruplexes (G4s) 1 (Fig. …

DNA and RNA can adopt various secondary structures. Four-stranded G-quadruplex (G4) structures form through self-recognition of guanines into stacked tetrads, and considerable …

Among these structures are G-quadruplex DNA structures (G4s), which support cellular function by affecting transcription, translation, and telomere maintenance. These structures can also …

Apr 18, 2013 · We propose that G4 motifs and structures that participate in key processes compose the G4 genome, analogous to the transcriptome, proteome, or metabolome. This is a …

Apr 8, 2025 · a, G4switch, a photoswitchable binder of DNA G4s, remains in the ‘OFF’ bent state (cis) in the dark or after green light deactivation at 525 nm, which does not favour …