Forkhead box protein A2 (FOXA2), also known as hepatocyte nuclear factor 3-beta (HNF-3B), is a transcription factor that plays an important role during development, in mature tissues and, …

Mar 30, 2025 · FOXA2 (Forkhead Box A2) is a Protein Coding gene. Diseases associated with FOXA2 include Combined Pituitary Hormone Deficiency and Hyperinsulinemic Hypoglycemia, …

Apr 11, 2024 · FOXA1 and FOXA2 have much crosstalk in steroid-hormone-associated cancers, for example, signaling pathways, epigenetic modifications, and post-translational …

Mar 1, 2011 · FOXA2 is a gene that plays a crucial role in the development and differentiation of dopamine neurons in the midbrain. It is expressed in the floor plate and is necessary for the …

Nov 14, 2022 · We identify that FOXA2 orchestrates prostate cancer adeno-to-neuroendocrine lineage transition and that Foxa2 expression is significantly induced by androgen deprivation. …

Dec 23, 2004 · Here we show that in normal mice, plasma insulin inhibits the forkhead transcription factor Foxa2 by nuclear exclusion and that in the fasted (low insulin) state Foxa2 …

Here we investigate the contribution of FOXA2 to coordinating intestinal epithelial cell function using postconfluent Caco2 cells, differentiated into an enterocyte-like model.

Feb 8, 2025 · Title: FOXA2 activates HIF2α expression to promote tumor progression and is regulated by the E3 ubiquitin ligase VHL in renal cell carcinoma. FOXA2 suppresses …

Feb 7, 2008 · Foxa2 regulates the expression of sonic hedgehog (Shh), which in turn activates gli1/2 and foxa2. Foxa2, Msx1, and Wnt1 regulate directly or indirectly the expression of …

FOXA2 controls the anti-oxidant response in FH-deficient cells. FOXA2 suppresses PKM2 transcription and affects the Wnt/beta-catenin activity to block aerobic glycolysis in thyroid …