Apr 23, 2016 · Fatp1 (B-/-) chimeras fed a HFD gained more epididymal white adipose mass, which was inflamed and oxidatively stressed, compared to HFD-fed Fatp1 (B+/+) controls. …

Mar 20, 2016 · FATP1 exacerbated pro-inflammatory activation in vitro and increased local and systemic components of the metabolic syndrome in HFD-fed Fatp1B / mice. In contrast, gain …

Sep 21, 2020 · Restricting CD36 either at palmitoylated or depalmitoylated state abolishes its FA uptake activity. Importantly, blocking the endocytosis significantly inhibits CD36-dependent FA …

Jan 8, 2025 · The endocannabinoid system shifts energy balance toward storage and fat accumulation, especially in the context of diet-induced obesity. Relatively little is known about …

Nov 3, 2021 · In this study, we observed that Prdm16 and FATP1 in WAT were upregulated by WA, and this was blocked by sympathetic denervation. The inhibition of Prdm16 or FATP1 in …

FATP1 mediates skeletal muscle cell fatty acid import, yet its intracellular localization and metabolic control role are not completely defined. Here, we examine FATP1 localization and …

May 1, 2013 · In FATP1-deficient mice, less accumulation of intramuscular fatty acyl-CoA was observed under a high-fat-diet (HFD)-fed condition, which made them less insulin resistant. 2 …

Vascular endothelial growth factor B (VEGF-B) regulates this process by controlling the expression of endothelial fatty acid transporter proteins (FATPs). Here, we summarize …

We hypothesized that specific lipid trafficking proteins, e.g. fatty acid transport protein 1 (FATP1), would direct MΦ fatty acid transport and metabolism to limit inflammation and contribute to the …

Jun 17, 2016 · We demonstrate that the response of fatty acid transporters to insulin stimulation is extremely brief and not temporally matched in the postprandial state. We further show that …