Apr 15, 2024 · Shell cross-linking of F127 micelles using APTES molecules. Controlled Vanc and QC drugs release over 168 h. Enhanced antibacterial and antioxidant activities by co-administration of two drugs. Bacterial infection is one of the …

Feb 2, 2017 · The amine-, carboxyl-, N-hydroxysuccinimide ester-, maleimide- and biotin-terminated Pluronic F127 allows ligand immobilization on single-emulsion or double-emulsion droplets via electrostatic adsorption, covalent conjugation or site-specific avidin-biotin interaction.

Sep 1, 2017 · Poloxamer 407 is an amphiphilic triblock copolymer with the ability to undergo a reversible thermal sol-gel transition. It is commercially available as Pluronic F127 (hereafter referred to as F127).

Poly lactic coglycolic acid (PLGA) was used to encapsulate different concentrations of sorafenib by a simple modified solvent evaporation method applying pluronic F-127 as a surfactant and...

The aldehyde-terminated F127 can form hydrogels with amines via Schiff bases and is commonly used for full-thickness skin wounds, joint wounds, diabetic wounds, burn wounds and skin tumors.

Jan 1, 2022 · Pluronic F127 (F127) was activated by grafting a hydrophobic and self-immolative linker so that hydrophilic amine-containing colistin was able to crosslink with modified F127, thus forming SIR-micelles via one-pot synthesis method, followed by removal of free surfactant by ultracentrifugation at low temperature [[30], [31], [32], [33]]. The ...

Aug 12, 2019 · Some synthetic polymers such as poly (N -isopropylacrylamide) (pNIPAAm), pluronics ® or poloxamers mainly Pluronic F-127 (PF127) are capable of showing sol-gel transition near the body...

The amine derived Pluronic F127 exhibits a broad signal at 2.434 ppm, which indicates the presence of terminal amine groups.

Apr 7, 2024 · We expect that our PLGA-F127 MS could be employed to extend the release period of 2 months of medication to 4 months. This could be a valuable solution for developing novel SRDDS for local injections. Keywords: PLGA drug; local …

Nov 13, 2018 · We report on a technologically accessible surface passivation and chemical conjugation method based on an NHS end-labeled F127 Pluronic block copolymer (F127-NHS).