Mar 15, 2017 · From what I can tell, you are having more trouble with the acidic hydrolysis of an enol ether to an aldehyde. As has been pointed out by some comments, your proposed …

Apr 13, 2015 · Some argue that the reaction actually proceeds through the ketal (rather than the hemiketal) since ketals can be isolated in these reactions. Others argue that just because the …

Jun 7, 2017 · I am having trouble understanding how the protecting group (ethylene glycol) is applied to the alkene next to the ether of highlighted step above. I thought maybe TsOH …

Mar 10, 2017 · That intermediate explains the need for aqueous $\ce{H+}$. Similarly to how the intermediate shown in the question wouldn't be my first guess (or, apparently, yours), I'm …

Apr 26, 2019 · I am forming silyl enol ethers using Chloro(trimethyl)silane (TMSCl), and below is an experimental protocol I am following. Silyl Enol Ether Synthesis. In an oven-dried 100 mL …

Jun 1, 2015 · Mechanism of enol ether formation. Ask Question Asked 9 years, 10 months ago. Modified 9 years, 10 months ago.

Mar 4, 2021 · Mechanism of enol ether formation. 1. Relative basicity of fluorine and oxygen in silyl ether deprotection. 7.

Oct 10, 2023 · Removal of the thioenol ether protecting group gives the aldehyde function, and under the acidic conditions the β-hydroxy group eliminates to give the mainly (E)-unsaturated …

Feb 25, 2019 · Thus, whether the nucleophile is very strong and basic, in the case of an aza-enolate, or relatively weaker, in the case of a silyl enol ether, the alkylation would still proceed …

Apr 25, 2018 · Mechanism for reaction of enol ether with HBr. Ask Question Asked 6 years, 11 months ago.