005628 B6.129S2- Emx1 tm1(cre)Krj /J Emx1-IRES-Cre knock-in mice have the endogenous Emx1 locus directing expression of Cre recombinase to approximately 88% of the neurons of …

Jul 5, 2000 · Furthermore, we have determined that the recombination efficiency in the cerebral cortex was 91%. Our results suggest that Emx1 is not expressed in every neuron in the …

Aug 1, 2002 · By homologous recombination of an internal ribosome entry site and Cre recombinase coding region into the 3′-untranslated region of the mouse Emx1 gene, we have …

Oct 16, 2024 · We recently generated Larp7 knockout mice using either Emx1-Cre or nestin-Cre (hereafter Emx1-Larp7-KO and Nestin-Larp7-KO, respectively) to examine the effect of Larp7 …

Emx1-IRES-Cre mice are widely used to dissect critical circuitry underlying neurologic disorders such as epilepsy. These studies often assume the Cre is expressed selectively in forebrain …

Jul 31, 2020 · Emx1Cre mediates recombination in cortical NPCs starting at E10.5 25, near the onset of excitatory neurogenesis, thus affecting subsequent NPCs, neurons, and astrocytes of …

Jul 5, 2000 · We reported previously the creation of a line of transgenic mice in which the cre gene was placed directly downstream of the putative Emx1 promoter using ES cell technology. …

Emx1 is a mouse homologue of the Drosophila ho-meobox gene empty spiracles and its expression is re-stricted to the neurons in the developing and adult cerebral cortex and …

This allele was derived from Emx1 tm1(cre)Ito by FLP recombinase excision of a FRT-flanked pgk-neo cassette that lay immediately downstream of the nls-cre gene. The Emx1 promoter …

Aug 1, 2002 · Our results demonstrate that radial glia, Cajal-Retzius cells, glutamatergic neurons, astrocytes, and oligodendrocytes of most pallial structures originate from an Emx1-expressing …