5 days ago · EBV encoded RNA Nuclear RNA portions of EBER1 and 2 genes Interpretation: nuclear stain

Four hematopathologists independently interpreted EBV-encoded RNA (EBER) and latent membrane protein 1 (LMP1) histochemical stains from 40 cases of Hodgkin lymphoma and then reviewed the stains as a group to resolve discrepancies and to develop interpretation guidelines.

Epstein-Barr encoding region (EBER) in situ hybridization is the methodology of choice for the detection of the Epstein-Barr virus (EBV) in tissue sections. Because of the large numbers of copies of EBERs present in latently infected cells, non-isotopic methods can be used.

Use to detect Epstein-Barr virus in paraffin. Does not include interpretation. Indicates whether a test has been approved by the New York State Department of Health. This test is New York state approved. Patient Preparation Instructions patient must follow before/during specimen collection. Collect Specimen type to collect.

EBER in situ hybridization remains the most reliable histochemical assay to localize EBV in these cancer tissues. Technical problems can foil interpretation of immunohistochemical results.

* Positive staining for LMP1 or EBER in a single RS cell is sufficient enough to make a diagnosis of EBV associated Hodgkin lymphoma. * The cytoplasm and the surface membrane of the RS cells show LMP1 staining and appear granular.

INFORM EBER (Epstein-Barr Virus Early RNA) Probe is intended for laboratory use in the qualitative in situ hybridization (ISH) detection of cells expressing Epstein-Barr encoded RNA (EBER) by light microscopy in sections of formalin-fixed, paraffin-embedded tissue stained on a BenchMark IHC/ISH instrument.This product should be interpreted by a ...

Jan 1, 2013 · Epstein–Barr encoding region (EBER) in situ hybridization is the methodology of choice for the detection of the Epstein–Barr virus (EBV) in tissue sections. Because of the large numbers of copies of EBERs present in latently infected cells, non-isotopic methods can be used.

Feb 1, 2002 · Four hematopathologists independently interpreted EBV-encoded RNA (EBER) and latent membrane protein 1 (LMP1) histochemical stains from 40 cases of Hodgkin lymphoma and then reviewed the...

Epstein-Barr virus (EBV) is the causative agent of infectious mononucleosis, and it may also be found in a wide variety of benign and malignant lesions including oral hairy leukoplakia, inflammatory pseudotumor, Hodgkin's disease, non-Hodgkin's lymphoma, nasopharyngeal carcinoma, and gastric carcinoma.