MTF2 facilitates the advancement of osteosarcoma through mediating EZH2 ...
Aug 8, 2024 · Co-immunoprecipitation (Co-IP) assay confirmed MTF2-EZH2 interaction. MTF2 expression was increased in osteosarcoma tissues and cells. MTF2 interference effectively …
MTF2 recruits Polycomb Repressive Complex 2 by helical-shape ... - Nature
May 28, 2018 · MTF2 directly binds to DNA and is essential for recruitment of PRC2 both in vitro and in vivo. Genome-wide recruitment of the PRC2 catalytic subunit EZH2 is abrogated in Mtf2 …
MTF2 facilitates the advancement of osteosarcoma through mediating EZH2 ...
Aug 8, 2024 · MTF2 interference effectively inhibited the proliferation, migration and invasion of osteosarcoma cells and promoted the cellular apoptotic rate. MTF2 directly bound to EZH2 …
MTF2 recruits Polycomb Repressive Complex 2 by helical-shape …
MTF2 directly binds to DNA and is essential for recruitment of PRC2 both in vitro and in vivo. Genome-wide recruitment of the PRC2 catalytic subunit EZH2 is abrogated in Mtf2 knockout …
Comprehensive Pan-Cancer Analysis of MTF2 Effects on Human …
Jun 1, 2023 · Studies have found that genome-wide recruitment of the PRC2 catalytic subunit EZH2 is abrogated in Mtf2 knockout cells, resulting in greatly reduced H3K27me3 deposition.
MTF2 metal response element binding transcription factor 2
Feb 8, 2025 · MTF2 facilitates the advancement of osteosarcoma through mediating EZH2/SFRP1/Wnt signaling. Tissue-Specific Tumour Suppressor and Oncogenic Activities of …
MTF2 facilitates the advancement of osteosarcoma through mediating EZH2 ...
MTF2 interference effectively inhibited the proliferation, migration and invasion of osteosarcoma cells and promoted the cellular apoptotic rate. MTF2 directly bound to EZH2 and MTF2 silence …
Mtf2-PRC2 control of canonical Wnt signaling is required for
May 1, 2018 · Gene regulatory network (GRN) analysis demonstrated Mtf2 directly regulates Wnt signaling in erythroblasts, leading to activated canonical Wnt signaling in Mtf2-deficient …
EZH2 - MTF2 Interaction Summary | BioGRID - thebiogrid.org
The Polycomb group proteins foster gene repression profiles required for proper development and unimpaired adulthood, and comprise the components of the Polycomb-Repressive Complex 2 …
Loss of PRC2 subunits primes lineage choice during exit of ... - Nature
Nov 30, 2021 · Two distinct PRC2 complexes, PRC2.1 and PRC2.2, contain respectively MTF2 and JARID2 in embryonic stem cells (ESCs). In this study, we explored their roles in lineage …
- Some results have been removed