
E2F - Wikipedia
E2F is a group of genes that encodes a family of transcription factors (TF) in higher eukaryotes. Three of them are activators: E2F1, 2 and E2F3a. Six others act as repressors: E2F3b, E2F4 …
E2F transcription factors and their complementary roles during …
E2F transcription factors (TF) comprise a family of proteins that regulate the expression of genes required for S-phase progression, among others.
NAC1 Maintains Root Meristem Activity by Repressing the …
Here, we provide evidence to show that NAC1 maintains root meristem and root growth through directly repressing E2Fa transcription, and loss of NAC1 triggers up-regulation of the E2Fa …
Atypical E2Fs: new players in the E2F transcription factor family
Atypical E2F proteins represent an evolutionarily conserved branch of the E2F TFs family, in which the presence of a duplicated DBD provides these new E2F players the unique ability to …
The atypical E2F transcription factor DEL1 modulates growth
Jun 1, 2020 · Here, we report that DEL1 represses excessive SA accumulation and root growth inhibition of host plants upon RKN infection. Furthermore, lignin deposition was also shown to …
Emerging Role of E2F Family in Cancer Stem Cells - PMC
The E2F family of transcription factors (E2Fs) consist of eight genes in mammals. These genes encode ten proteins that are usually classified as transcriptional activators or transcriptional …
Distinctive and complementary roles of E2F transcription factors …
Here, we report the roles of the Arabidopsis E2FA and EF2B transcription factors, two well-characterized regulators of DNA replication, in plant response to replication stress.
Negative regulator of E2F transcription factors links cell cycle ...
In this study, we demonstrated that the DNA repair protein SNI1, a subunit of SMC5/6 complex, is a negative regulator of E2Fs. In addition, this study also suggests that checkpoint and DNA …
Atypical E2Fs: new players in the E2F transcription factor family
Feb 9, 2009 · Atypical E2F proteins represent an evolutionarily conserved branch of the E2F TFs family, in which the presence of a duplicated DBD provides these new E2F players with the …
E2Fb and E2Fa transcription factors independently regulate the …
Nevertheless, in UV-B-exposed seedlings, E2Fa, but not E2Fb, regulates primary root elongation, cell proliferation, and programmed cell death in the meristematic zone. Using e2fa mutants …