May 24, 2022 · The morphologic, immunophenotypic and cytogenetic findings are diagnostic of DLBCL, NOS, with a germinal center B cell phenotype (answer C). Per the Hans algorithm, CD10 positivity in DLBCL is predictive of a germinal center B cell subtype gene expression profile.

CD21 stain shows expanded follicular dendritic cell meshwork. EBV ISH is positive in scattered large B-cells. In extranodal NK/T-cell lymphoma, EBV positive cells are positive for CD3 and negative for CD79a in double stains.

Apr 24, 2023 · Diffuse large B cell lymphoma (DLBCL) is the most common lymphoma, accounting for about 25% to 30% of all the non-Hodgkin lymphomas. It typically presents as a rapidly growing mass or enlarging lymph nodes in a nodal or extranodal site.

Diffuse large B-cell lymphoma (DLBCL) is an aggressive type of non-Hodgkin's lymphoma (NHL) that develops from the B-cells of the lymphatic system. It is the most common subtype of NHL accounting for 30%–40% of all cases. In addition to determining ...

Diffuse large B-Cell lymphoma (DLBCL) may infiltrate bone marrow (BM) and evaluation of BM plays an important role in DLBCL staging. This study used BM samples from DLBCL patients for staging and analyzed the use of immunohistochemistry in the diagnostic management of these cases by the pathologist.

5 days ago · DLBCL / high grade B cell lymphoma with MYC and BCL2 rearrangements. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lymphomabunclassburkitt.html. Accessed April 15th, 2025. Which of the following is confirmation of double hit …

Mar 29, 2017 · Diffuse large B-cell lymphoma, abbreviated DLBCL, is a very common lymphoma with a poor prognosis.

Sep 6, 2022 · HHV8 related diffuse large B cell lymphoma (DLBCL) is a neoplasm characterized by a monoclonal proliferation of HHV8 infected lymphoid cells resembling plasmablasts expressing IgM lambda

Diagnosis: DLBCL is ideally diagnosed from an excisional biopsy of a suspicious lymph node, which shows sheets of large cells that disrupt the underlying structural integrity of the follicle center and stain positive for pan-B-cell antigens, such as CD20 and CD79a.

Mar 25, 2022 · In addition, DLBCL-Morph contains 204 digital high-magnification whole-slide images (WSIs) from 149 DLBCL cases, stained for H&E. A total of 152,194 patches (240x240 pixels each) were extracted from the H&E stained ROIs and a HoVer-Net model was used to segment tumor nuclei (1,035,909 binary masks).