DIOP (Product No. 237655; [(-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane]) is a C 2 chelating diphosphine ligand for transition metal …

Apr 6, 2004 · The chiral ligand modifies the reactivity and selectivity of the metal center in such a way that one of two possible enantiomeric products is formed preferentially. Based on this …

Jul 26, 2004 · Several DIOP derivatives have been developed as efficient ligands for Rh and Ir-catalyzed asymmetric hydrogenations. The conformational mobility of the backbone in this …

Mar 18, 2004 · The most common ligands have a chiral backbone with two coordinating heteroatoms. The pioneering work by Kagan, who reported the first chiral biphosphine ligand …

Apr 4, 2004 · Achiwa and coworkers have illustrated this by desymmetrizing the DIOP ligand (Fig. 4). Indeed, replacing one of the diphenylphosphine units by a more electron-rich …

The C2-symmetric ligand DIOP (Fig. 2) was introduced by Dang and Kagan in 1971 (6). The reason for choosing a C2-symmetric ligand with two equivalent P atoms was to reduce the …

May 17, 2007 · The successful development of three classes of ligands is presented, including (1) ligands with phosphocyclic motifs, (2) ligands with atropisomeric backbones, and (3) …

Substituent changes in the ligand (L*) backbone and the chelating phosphorus atoms of the classical DIOP ligand result in dramatic changes in the enantioselectivity of Rh + L*-catalyzed …

Jan 27, 2025 · It also finds it application for the in situ preparation of chiral hydrogenation catalysts, ligand for Rh(I)-catalyzed asymmetric hydrogenation of enamides, 1,4-disilylation of …

DIOP ligand plays an important role in improving the activity, selectivity and stability of transition metal catalysts through its diphosphorus structure, electron donation effect and steric effect. It …