DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor …

Death-Associated Protein Kinase 1 (DAPK1) belongs to a family of five serine/threonine (Ser/Thr) kinases that possess tumor suppressive function and also mediate a wide range of cellular …

Mar 28, 2025 · DAPK1 (Death Associated Protein Kinase 1) is a Protein Coding gene. Diseases associated with DAPK1 include Pancreatic Ductal Adenocarcinoma and Cervical Squamous …

Jun 23, 2016 · DAPK1 is an important regulator of cell death and autophagy which act as a critical component in the ER stress-induced cell death pathway (Gade et al., 2014).

DAPK1 is a central signal transducer in different pro-apoptotic pathways that are connected with various cell death mechanisms, and is activated by various external and internal apoptotic …

Death-Associated Protein Kinase 1 (DAPK1) plays an important role in apopto-sis, tumor suppression and neurodegeneration including Alzheimer’s Disease (AD). This review will …

May 4, 2020 · Death-associated protein kinase 1 (DAPK1, DAPk, DAPK) is known for its involvement in apoptosis and autophagy-associated cell death. Here, we identified an …

The absence of DAPK1 promotes efficient learning and better memory in mice and prevents the development of AD by acting on many key proteins including Pin1 and its downstream targets …

Jan 9, 2024 · Death-associated protein kinase 1 (DAPK1) is ubiquitously expressed in the central nervous system. Dysregulation of DAPK1 has been shown to contribute to various …

Mar 8, 2021 · Death-associated protein kinase (DAPK1) and DAP (600954) are positive mediators of the programmed cell death induced by gamma-interferon (IFNG; 147570). The inactivation …