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Genes¶ The gene entity within the CIViC database includes several useful features for assessing the clinical relevance of variants (Figure 1). The first is a human curated gene-level summary …

View Gene Curation Docs . Browse All Features . Name Full Name Type Aliases Diseases Therapies Count

CIViC variants are usually genomic alterations, including single nucleotide variants (SNVs), insertion/deletion events (indels), copy number alterations (CNVs; such as amplifications or …

Genes are identified within CIViC using Entrez Gene names and IDs. Once a gene record exists it is automatically linked (via Entrez Gene) to additional gene-level details using the mygene.info …

These videos cover CIViC and its goals; finding documentation and help resources; browsing and searching knowledgebase contents; adding new evidence, variant summaries, coordinates, …

CIViC is an open access, open source, community-driven web resource for Clinical Interpretation of Variants in Cancer. Our goal is to enable precision medicine by providing an educational …

CIViC Molecular Profiles are combinations of one or more CIViC variants. Most Molecular Profiles are “Simple” Molecular Profiles comprised of a single variant. In most cases, these can be …

CIViC. Evidence Level. The type of experiment from which the evidence is curated. From inferential, to proven association in clinical medicine. Refer to the additional documentation on …

Jan 31, 2017 · CIViC is an expert-crowdsourced knowledgebase for Clinical Interpretation of Variants in Cancer describing the therapeutic, prognostic, diagnostic and predisposing …