Chemokines (from Ancient Greek χῠμείᾱ (khumeíā) 'alchemy' and κῑ́νησῐς (kī́nēsis) 'movement'), or chemotactic cytokines, are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells. [1][2] In addition to playing a m...

The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are best known for their ability to stimulate the migration of cells, …

Jul 4, 2017 · Chemokines are signaling proteins secreted by cells of the immune system that stimulate the movement of other cells. Their name is reminiscent of their function since it is derived from chemotaxis, or movement in response to a chemical stimulus, and cytokines, which are small proteins implicated in cell signaling.

Chemokines are a family of chemoattractant cytokines (small proteins secreted by cells that influence the immune system) which play a vital role in cell migration through venules from blood into tissue and vice versa, and in the induction of cell movement in response to a chemical (chemokine) gradient by a process known as chemotaxis (Figure 1 ...

chemokine, any of a group of small hormonelike molecules that are secreted by cells and that stimulate the movement of cells of the immune system toward specific sites in the body.

Feb 1, 2000 · Chemokines are a group of small (∼8–14 kDa), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of seven-transmembrane, G protein–coupled receptors. About 40 chemokines have now been identified in humans.

Sep 2, 2022 · Chemokines are a large subfamily of small cell signaling proteins or cytokines, which in conjunction with their G protein-coupled receptors (GPCR), govern the process of cell migration.

Feb 12, 1998 · Chemokines are 8-to-10-kd proteins with 20 to 70 percent homology in amino acid sequences. They have been subdivided into families on the basis of the relative position of their cysteine...

Chemokines or chemotactic cytokines are a family of small molecular weight proteins that promote directional migration of leukocytes, endothelial and epithelial cells. Chemokines are classified into CXC, CC, CX 3 C or C chemokines based on the positioning of the conserved cysteine residues [1, 2].

Five years ago, very few people knew much about chemokines. Interest in these small proteins centred on their role as chemoattractants that recruit phagocytic cells from the blood to local sites of infection.