Aug 25, 2022 · This is the first demonstration in fish that ceRNA crosstalk mediated by ncRNAs modulates sexual development and unveils a novel regulatory mechanism for sex determination and differentiation.

Jan 15, 2014 · Understanding this novel RNA crosstalk will lead to significant insight into gene regulatory networks and have implications in human development and disease. In recent years, numerous studies...

However, the ceRNA crosstalk in CRSwNP is still unclear METHODS: We investigated expression profiles of messenger RNA (mRNA), microRNAs (miRNAs), and long noncoding RNAs (lncRNAs) in eosinophilic CRSwNP and constructed a global triple ceRNA network.

Functional interactions in ceRNA networks aid coordinating a number of biological processes and, when perturbed, contribute to disease pathogenesis. In this review, we discuss recent discoveries that implicate natural miRNA decoys in the development of cancer. Diseases such as cancer are often associated with aberrant transcriptomes.

In this review, we present a genome-wide molecular interaction dominated by ncRNAs in a deep-going extent of post-transcriptional regulation regarding different types of cancer, where detailed mechanisms of the dynamic network, powerful predicting tools, and typical ceRNA crosstalk in pathogenesis, progression, and drug resistance in cancer ...

In this Review, we focus on the emerging roles of RNA–RNA crosstalk, which include new layers of gene regulation that involve interactions between diverse RNA species. A classic example of...

Mar 23, 2018 · In this review, we draw upon existing data to highlight mechanistic and theoretical aspects of ceRNA crosstalk. Our intent is to propose how understanding of ceRNA crosstalk mechanisms can be improved and what evidence is required to demonstrate a …

Apr 1, 2022 · Here, we constructed the landscape of the ceRNA-mediated pathway–pathway crosstalk of eight major cardiovascular diseases (CVDs) based on sequencing data from ∼2,800 samples. Some common features shared by numerous CVDs were uncovered.

Jan 16, 2014 · Understanding this novel RNA crosstalk will lead to significant insight into gene regulatory networks and have implications in human development and disease.

Functional interactions in ceRNA networks aid in coordinating a number of biologic processes and, when perturbed, contribute to disease pathogenesis. In this review, we discuss recent discoveries that implicate natural miRNA decoys in the development of cancer.