Integrin alpha 2b - Wikipedia
Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. ITGA2B, also known as CD 41, encodes integrin alpha chain 2b. Integrins are heterodimeric integral …
Different expression of CD41 on human lymphoid and myeloid progenitors ...
Apr 1, 2001 · To investigate the precise expression of the CD41 antigen during megakaryocyte (MK) differentiation, CD34 + cells from cord blood and mobilized blood cells from adults were …
Anti-CD41 Antibodies | Invitrogen - Thermo Fisher Scientific
CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive …
CD41a Monoclonal Antibody (HIP8) (14-0419-82) - Thermo Fisher Scientific
Invitrogen Anti-CD41a Monoclonal (HIP8), eBioscience™, Catalog # 14-0419-82. Tested in Immunohistochemistry (IHC) and Flow Cytometry (Flow) applications. This antibody reacts …
Flow cytometric analysis of platelet surface glycoproteins in the ...
Glanzmann thrombasthenia (GT) is a rare autosomal recessively inherited bleeding disorder characterized by the quantitative (type 1 and type 2) or qualitative (type 3) deficiency in …
ITGA2B Gene - GeneCards | ITA2B Protein | ITA2B Antibody
Mar 30, 2025 · ITGA2B (Integrin Subunit Alpha 2b) is a Protein Coding gene. Diseases associated with ITGA2B include Glanzmann Thrombasthenia 1 and Bleeding Disorder, …
CD41 expression marks myeloid-biased adult hematopoietic stem …
May 30, 2013 · Integrin CD41, thought to absent on adult HSCs, marks a novel subset of myeloid-biased long-term HSCs that becomes prevalent with age. Loss of CD41 leads to …
CD41 is developmentally regulated and differentially expressed …
May 12, 2011 · CD41 expression is associated with the earliest stages of mouse hematopoiesis. It is notably expressed on some cells of the intra-aortic hematopoietic clusters, an area where …
Expandable Megakaryocyte Cell Lines Enable Clinically Applicable ...
Apr 3, 2014 · In the present study, we show that co-overexpression of c-MYC and BMI1, a polycomb complex component that represses the INK4A/ARF gene locus (Oguro et al., 2006), …
Interactions with and activation of immune cells by CD41a
Feb 14, 2025 · CD4 + TLs required large numbers of CD41a + EVs for activation, whereas monocytes were the most sensitive. With the new multi-omics technique, we confirmed the …