CD16 expression enables antibody-mediated degranulation and thus allows T cell receptor-independent cytotoxicity. In patients with severe COVID-19, CD16-positive T cells may lead to …

CD16 is the low-affinity IgG Fc receptor (FcγRIII-A) expressed on NK cells. Its crosslinking activates the PI3K pathway and induce the release of cytotoxic granules leading to antibody …

Activated NK cells loose CD16 (FcRγIII) and CD62L through a metalloprotease called ADAM17. Inhibition of ADAM17 enhances CD16 mediated NK cell function by preserving CD16 on the …

CD16, a key player in immune regulation, exemplifies the intricate and dynamic interactions within the immune system. Its involvement in processes like ADCC, phagocytosis, and modulation of …

Sep 27, 2016 · We found that human CD16− expressing monocytes have a broad spectrum of ADCC capacities and can kill cancer cell lines, primary leukemic cells and hepatitis B virus …

The Relationship of CD16 (Leu-11) and Leu-19 (NKH-1) Antigen Expression on Human Peripheral Blood NK Cells and Cytotoxic T Lymphocytes. J Immunol (1986) 136:4480–6.

CD16, also known as FcγRIII, refers to a cluster of differentiation molecule found on the surface of various immune cells, including natural killer cells, neutrophils, monocytes, macrophages, and …

The role of epigenetic regulatory mechanisms controlling transcriptional and post-transcriptional CD16 expression in NK cells is unknown. Here we compared specific patterns of DNA …

Sep 27, 2016 · Antibody-dependent cellular cytotoxicity (ADCC) is exerted by immune cells expressing surface Fcγ receptors (FcγRs) against cells coated with antibody, such as virus …

CD16 is a low affinity IgG receptor found on various immune cells such as natural killer cells and T-cells. It plays a role in antibody-dependent cell-mediated cytotoxicity and is also expressed …