The link between EMT and immune recognition and killing of cancer cells is well established. EMT contributes to immune escape of tumors as it has been demonstrated in the human mammary …

In cancers, EMT inducers are hypoxia, cytokines, and growth factors secreted by the tumor microenvironment, stroma crosstalk, metabolic changes, innate and adaptive immune …

Jan 12, 2018 · Similar to embryonic development, changes in cell phenotypes defined as an epithelial to mesenchymal transition (EMT) have been shown to play a role in the tumorigenic …

Sep 8, 2022 · Mesenchymal carcinoma expressing EMT markers exert immunosuppressive effects in multiple ways, including secreting chemokines and cytokines, thus promoting the …

Carcinosarcoma is the tumor best studied, in which monoclonality of both epithelial and mesenchymal cell components strongly favors an EMT. A challenging hypothesis considers …

Nov 20, 2018 · Epithelial–mesenchymal transition (EMT) is crucial for embryogenesis, wound healing and cancer development, and confers greater resistance to cancer therapies.

In carcinoma progression, EMT plays a crucial role in early steps of metastasis when cells lose cell-cell contacts due to ablation of E-cadherin and acquire increased motility to spread into …

Using various cancer models, Ricciardi and colleagues observed that exposure to inflammatory cytokines can endow cancer cells undergoing EMT with a number of immunomodulatory …

Apr 2, 2025 · The epithelial-mesenchymal transition (EMT) is a critical process in cancer progression, facilitating tumor cells to develop invasive traits and augmenting their migratory …

Similar to embryonic development, changes in cell phenotypes defined as an epithelial to mesenchymal transition (EMT) have been shown to play a role in the tumorigenic process. …