CA 72-4, also known as cancer antigen 72-4, is a protein that is commonly found in high levels in the blood of individuals with certain types of cancer, most notably gastrointestinal and ovarian cancers.

This study aims to investigate the role of serum cancer antigen 72-4 (CA72-4) in the diagnosis of GC in a healthy population. A total of 7757 adults who underwent upper gastrointestinal endoscopy and serum CA72-4 level measurement in multicenters in Taiwan from January 2006 to August 2016 were recruited in this retrospective study.

Dec 1, 2021 · The role of conventional serum tumor marker, carbohydrate antigen 72–4 (CA72-4), in assisting diagnosis, monitoring dynamic progression, and evaluating the prognosis of gastric cancer (GC) should not be ignored, especially in the Chinese population.

Several studies focused on the potential clinical usefulness of CA 72-4 in gastrointestinal (GI) and gynecological cancer, showing a sensitivity of approximately 40% in colorectal and gastric cancer and 50% in ovarian cancer, with an overall specificity of more than 95%.

Mar 21, 2017 · CA72-4 is a tumor marker (TM) that has been found elevated in a variety of human adenocarcinomas, with reported sensitivities of up 50% and overall specificity of over 95%. Using the DRG TM-CA72-4 assay, we quantified the abnormality rate of TM CA72-4 compared with current FDA-approved TM in various cancers.

Oct 2, 2024 · CA 72-4, initially identified in 1981 as an antigen reactive to murine antibodies, is a glycoprotein expressed on the cell surface of certain carcinoma cells. Its production is elevated in various cancers, including ovarian, pancreatic, colorectal, and gastric cancer.

CA 72-4 was first identified by Colcher in 1981 and has since been identified as a tumor-associated glycoprotein-72 antigen (TAG-72) in several epithelial cancers. Several recent studies have demonstrated the usefulness of CA 72-4 in the diagnosis and prognosis of gastric cancer.

In gastric cancer, the most used tumor markers are: CA 72-4, carcinoembryonic antigen (CEA) and cancer-related antigen 19-9 (CA 19-9). Cancer-related antigen 72-4. CA 72-4 is a glycoprotein found on the surface of tumor cells, with a weight of 200–420 kDA .

The role of conventional serum tumor marker, carbohydrate antigen 72-4 (CA72-4), in assisting diagnosis, monitoring dynamic progression, and evaluating the prognosis of gastric cancer (GC) should not be ignored, especially in the Chinese population.

These preliminary findings indicate that CA72-4 is a reliable tumour marker of disease stage and activity in gastric cancer. Further longitudinal studies are required for full evaluation of its clinical utility. To date, tumour markers for gastric cancer have proved unreliable.