
The role of complement regulatory proteins (CD55 and CD59) in …
Two of these regulators in humans, CD55 and CD59, are glycosylphosphatidylinositol-anchored, type I cell surface proteins, which inhibit formation of the C3 convertases and prevent the …
Beyond the Role of CD55 as a Complement Component - PMC
Decay-accelerating factor (DAF or CD55) is a known inhibitor of the complement system and has recently attracted substantial attention due to its role in various diseases, such as cancer, …
Expression of CD55 and CD59 on peripheral blood cells from
CD55 and CD59 are glycosylphosphatidylinositol-anchored proteins with complement inhibitory properties. CD55 inhibits the formation of C3 convertases, and CD59 prevents the terminal …
CD55 vs. CD59 - What's the Difference? | This vs. That
CD55 and CD59 are both cell surface proteins that play crucial roles in regulating the complement system, which is a part of the immune system. CD55, also known as decay-accelerating factor …
Abnormalities in the expression of CD55 and CD59 surface ... - PubMed
We conclude that the diminished expression of the glycolsylphosphatidylinositol-anchored type I cell surface proteins CD55 and CD59 is not specific to PNH and that it can be found in patients …
CD59 deficiency is associated with chronic hemolysis and …
Jan 3, 2013 · CD59 deficiency is a common finding in RBCs and WBCs in patients with chronic hemolysis suffering from paroxysmal nocturnal hemoglobinuria in which the acquired mutation …
Adeno-Associated Virus Mediated Delivery of An Engineered …
CD46, CD55 and CD59 are the major membrane associated regulators of complement on human cells. Previously, we have found that independent expression of CD55, CD46 or CD59 through …
Silencing EGFR-upregulated expression of CD55 and CD59
Oct 21, 2022 · These findings underscore the critical role of EGFR/Wnt/β-catenin-upregulated CD55/CD59 expression in inhibiting the complement and CD8 + T cell activation for tumor …
Expression levels of complement regulatory proteins (CD35, CD55 …
CD35, CD55 and CD59 regulate the complement system, and changes in their expression have previously been linked with kidney disease. This study assessed whether changes in the …
The role of complement regulatory proteins (CD55 and CD59) …
Jan 1, 2007 · In this study, we evaluated the membrane density of CD55 and CD59 in erythrocytes from patients with autoimmune hemolytic anemia (AIHA) and its possible relation …