CD4 T cell-intrinsic role for the T helper 17 signature cytokine IL-17 ...
Aug 11, 2020 · CD4+ T helper 17 (Th17) cells, characterized by IL-17 production, play important roles in the pathogenesis of autoimmune diseases (such as arthritis, multiple sclerosis, …
A distinct lineage of CD4 T cells regulates tissue ... - Nature
Oct 2, 2005 · Interleukin 17 (IL-17) has been linked to autoimmune diseases, although its regulation and function have remained unclear. Here we have evaluated in vitro and in vivo the …
IL-17 Receptor C Signaling Controls CD4 - PubMed Central (PMC)
IL-17A–producing CD4 + T helper (T H 17) cells play a critical role in autoimmune and chronic inflammatory diseases, such as crescentic GN. The proinflammatory effects of IL-17 are …
Identification of IL-17-producing FOXP3 - PNAS
Mar 24, 2009 · In this study, we report that human peripheral blood and lymphoid tissue contain a significant number of CD4 + FOXP3 + T cells that express CCR6 and have the capacity to …
Interleukin 17-producing CD4+ effector T cells develop via a …
CD4(+) T cells producing interleukin 17 (IL-17) are associated with autoimmunity, although the precise mechanisms that control their development are undefined. Here we present data that …
IL-17 and IL-17-producing cells in protection versus pathology
IL-17A and IL-17F are produced by CD4 + and CD8 + T cells, γδ T cells, and various innate immune cell populations in response to IL-1β and IL-23, and they mediate protective immunity …
Interleukin 17–producing CD4+ effector T cells develop via a …
Oct 2, 2005 · CD4+ T cells producing interleukin 17 (IL-17) are associated with autoimmunity, although the precise mechanisms that control their development are undefined.
Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties
The range of identified effector CD4 T cell lineages has recently expanded with description of an IL-17-producing subset, called Th17, which develops via cytokine signals distinct from, and …
IL-17 cytokines preferentially act on naïve CD4 - PLOS
Apr 28, 2023 · Recent reports have brought to light that the IL-17 family cytokines, IL-17A, IL-17F and IL-17AF, can directly act on CD4+ T-cells, both in murine and human systems, inducing …
CD4 T cell-intrinsic role for the T helper 17 signature cytokine IL-17 ...
CD4+ T helper 17 (Th17) cells, characterized by IL-17 production, play important roles in the pathogenesis of autoimmune diseases (such as arthritis, multiple sclerosis, psoriasis, …
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