Apr 9, 2025 · Distinguish myeloid (CD33+) and lymphoid leukemias (CD33-) Identify monocytes by flow cytometry

CD33 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

CD33 (cluster of differentiation 33) is a transmembrane protein that is a member of the sialic acid-binding immunoglobulin-like lactic (Siglec) family. The exact function of CD33 is not known, but it may be involved in cell-to-cell adhesion.

CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage. [5] It is usually considered myeloid-specific, but it can also be found on some lymphoid cells.

Our CD33 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Rat and Alpaca. These antibodies have been verified by Cell treatment and Knockout to confirm specificity to CD33.

CD33 (SP266) Rabbit Monoclonal Primary Antibody is intended for laboratory use in the detection of the CD33 protein in formalin-fixed, paraffin-embedded tissue stained on VENTANA BenchMark IHC/ISH instruments.

CD33 (cluster of differentiation 33) is a transmembrane protein that is a member of the sialic acid-binding immunoglobulin-like lactic (Siglec) family. The exact function of CD33 is not known, but it may be involved in cell-to-cell adhesion.

In normal bone marrow, weak to moderate CD33 staining is seen on granulocytic and monocytic precursors, with strong staining in scattered mast cells. CD33 staining is useful for diagnosis of myeloid

CD33 or Siglec-3 is a 67 kD glycosylated transmembrane receptor expressed on myeloid-specific cells (1,2). In the past, CD33 was only used for flow cell cytometry. Recently, a CD33 for paraffin-embedded tissues has been developed and has been used to phenotype acute myelogenous leukemias (1,2).