PD-L1 - Wikipedia
Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene.
CD274 Gene - GeneCards | PD1L1 Protein | PD1L1 Antibody
Mar 30, 2025 · CD274, also commonly referred to as PDL1, is a ligand that binds with the receptor PD1, commonly found on T-cells, and acts to block T-cell activation. PD1 expression …
Clinicopathologic profile, immunophenotype, and genotype of CD274 …
Aberrantly expressed CD274 allows tumor cells to evade host immune system and is considered to be a mechanism of adaptive immune resistance. Inhibition of the CD274/PDCD1 immune …
CD274 CD274 molecule [Homo sapiens (human)] - Gene - NCBI
Feb 9, 2025 · Gene target information for CD274 - CD274 molecule (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
Tumour CD274 (PD-L1) expression and T cells in colorectal cancer
Objective: Evidence suggests that CD274 (programmed death-ligand 1, B7-H1) immune checkpoint ligand repress antitumour immunity through its interaction with the PDCD1 …
Gene code CD274/PD-L1 : from molecular basis toward cancer …
PD-L1, also known as B7 homolog 1 (B7-H1) or cluster of differentiation 274 (CD274), represents the first functionally characterized ligand of the co-inhibitory PD-1.
CD274 promotes cell cycle entry of leukemia-initiating cells …
Nov 17, 2016 · CD274 (programmed death ligand 1, also known as B7H1) is expressed in both solid tumors and hematologic malignancies and is of critical importance for the escape of …
Identification and characterization of novel CD274 (PD‐L1) …
MiRNA targets successfully downregulated CD274 and affected cell‐mediated cytotoxicity. The created ComPDM score utilizing the expression of CD274 ‐targeting miRNAs, CD274 …
CD274 CD274 molecule - NIH Genetic Testing Registry (GTR)
Nov 5, 2024 · Clinical resource with information about CD274, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, …
Clinicopathologic profile, immunophenotype, and genotype of CD274 …
The CD274 (PD-L1)/PDCD1 (PD-1) pathway is crucial for the modulation of immune responses and self-tolerance. Aberrantly expressed CD274 allows tumor cells to evade host immune …