
Pathology Outlines - CD23
May 21, 2024 · Differentiates small lymphocytic lymphoma (SLL) / chronic lymphocytic leukemia (CLL) (CD23+) from mantle cell lymphoma or MALT lymphoma (CD23-) B cell marker, …
Differential diagnosis of chronic lymphocytic leukemia/small ...
The CLL type is the most common (75% of all cases), and it is characterized by B-cell markers (CD19, CD20 (weak)), CD23, and CD5, and the B-cells exhibit light chain restriction or lack …
The clinical and diagnostic relevance of CD23 expression in
Mar 15, 2002 · Background: CD23 antigen is a cell surface protein considered important in the differentiation of chronic lymphocytic leukemia (CLL) from other lymphoid leukemias.
One of the most useful markers for identifying B-cell CLL (B-CLL) is the CD23 antigen, a low-affinity immunoglobulin (Ig) E receptor expressed on mature resting cells and some activated …
Monoclonal B-cell lymphocytosis and early-stage chronic …
Jul 23, 2015 · The immunophenotype profile of classic CLL is dim sIg and dim CD20; CD5 and CD23 expression (not partial expression for either) is critical. Some degree of …
Atypical Chronic Lymphocytic Leukemia—The Current Status
A diagnosis of typical chronic lymphocytic leukemia (CLL) requires the presence of ≥5000 clonal B-lymphocytes/μL, the coexistence of CD19, CD20, CD5, and CD23, the restriction of light …
CD23 and chronic lymphocytic leukemia - PubMed
The aim of this paper is to establish the link between CD23 and CLL disease and to propose that the CD23 molecule is not simply a marker of CLL disease but may also be involved in the …
The cut-off levels of CD23 expression in the differential ... - PubMed
Our results suggest that high values of CD23 positivity (>92.5%) and/or high fluorescence intensity (>44.5 mean fluorescence intensity (MFI)) of CD23 are related to CLL, whereas low …
Soluble CD23 (sCD23): A Forgotten Indicator of Prognosis and …
Dec 6, 2014 · The sCD23 is a 25kDa fragment that can be found in serum, plasma and urine in patients with chronic lymphocytic leukemia. Objective: To evaluate a novel and robust method …
CD23 antigen regulation and signaling in chronic lymphocytic leukemia ...
B lymphocytes from patients with chronic lymphocytic leukemia (B-CLLs), strongly express the CD23 antigen, a surface marker with significant prognostic importance in this disease.