CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels.

May 21, 2024 · CD23 is a low affinity IgE receptor Differentiates small lymphocytic lymphoma (SLL) / chronic lymphocytic leukemia (CLL) (CD23+) from mantle cell lymphoma or MALT …

This review summarizes recent data on CD23, a low affinity receptor for IgE (Fc epsilon RII). CD23 is the only FcR which does not belong to the immunoglobulin gene superfamily.

The lower-affinity IgE Fc receptor, CD23, has multiple functions in enhancing the ... The association of immunoglobulin E (IgE) with allergic diseases and asthma is well established. …

Dec 6, 2014 · The CD23 protein can be cleaved and released into the serum as a soluble form of CD23 (sCD23). The sCD23 is a 25kDa fragment that can be found in serum, plasma and urine …

39.5.2.2 CD23 (FcεRII): The Low-affinity Receptor for IgE. CD23 is a type II integral membrane protein with an extracellular C-terminal domain that is homologous to C-type lectins.

May 16, 2016 · We examined the expression of CD23 in different subsets of peripheral B cells and the impact of CD23 expression on the early events of B-cell receptor (BCR) activation …

The low affinity IgE receptor, Fc∊RII (CD23), is both a positive and negative regulator of IgE synthesis. The proteinase activity that converts the membrane-bound form of CD23 into a …

Here, we focus on CD23 and discuss several mechanisms related to IgE binding, as well as the impact of the IgE/antigen-binding on different immune cells expressing CD23. One recent …

CD23 is the low-affinity receptor for immunoglobulin (Ig)E and plays important roles in the regulation of IgE responses. CD23 can be cleaved from cell surfaces to yield a range of …