CD20 is a transmembrane protein consisting of four hydrophobic transmembrane domains, one intracellular domain and two extracellular loops. There are three different forms of CD20 according to variable phosphorylation.

Mar 26, 2025 · CD20 is a CD marker—a molecule on the cell surface that can be used to identify and type a particular cell in the body. CD20 is found on the surface of B cells (a type of …

Anti-CD20 monoclonal antibodies act through several mechanisms, including complement-dependent cytotoxicity (CDC), complement-dependent cellular cytotoxicity (CDCC), antibody-dependent cellular phagocytosis (ADCP), antibody-dependent cellular cytotoxicity (ADCC), and induction of direct apoptosis.

(1) Plasmablasts and stimulated plasma cells may express CD20. (2) CD20 is generally coexpressed on B cells with CD19, another B-cell differentiation marker. CD20 appears to play a role in B-cell development, differentiation, B-cell receptor (BCR) …

Sep 20, 2021 · CD20 is a common B cell marker also called L26, membrane spanning 4 domains (MS4A1).

CD20 encodes a B-cell membrane–spanning molecule important in B-cell proliferation and differentiation. It is expressed from early pre-B until mature B-cell stage but is lost on differentiation to plasma cell.

CD20 is a general B cell marker that is expressed during B cell differentiation from the pro-B cell phase until the plasma cell stadium. The physiological ligand and exact biological function of CD20 is currently unknown. In vitro studies propose a …

Feb 16, 2021 · CD20 is a B cell-specific membrane protein and represents an attractive target for therapeutic antibodies. Despite widespread usage of anti-CD20 antibodies for B cell depletion therapies, the biological function of their target remains unclear.

CD20 is a protein primarily expressed on the surface of B cells, a type of white blood cell that plays a key role in the immune system’s defense against infections.

CD20 is a cell surface protein primarily expressed on the surface of B-cells, a type of white blood cell involved in the immune response. The CD20 molecule plays a critical role in the development, differentiation, and function of B-cells, which are responsible for producing antibodies.