
Human blood monocyte subsets: a new gating strategy defined …
To improve the monocyte purity, we devised a new gating scheme that takes advantage of the shared coexpression of cell surface markers on each subset. In addition to CD14 and CD16, …
Human dendritic cell subsets - PMC
CD14+DCs found in tissues and lymph nodes are a third subset of CD11c + myeloid cells originally described as ‘interstitial DCs’. They are more monocyte-like or macrophage-like than …
Differential expression of CD11c defines two types of tissue
Jan 18, 2022 · CD11c + and CD11c − macrophages strongly expressed colony-stimulating factor (CSF)-1 receptor, the injection of an anti-CSF-1 receptor blocking antibody markedly reduced …
Human dendritic cell subsets: an update - PMC
Detailed phenotyping and single‐cell gene expression studies have recently characterized two subsets of cDC2 in human blood, one ‘DC‐like’ with higher expression of CD5, CD1c, HLA‐DQ …
Rapid accumulation of CD14+CD11c+ dendritic cells in gut …
Background: Of antigen-presenting cells (APCs) expressing HLA-DQ molecules in the celiac disease (CD) lesion, CD11c (+) dendritic cells (DCs) co-expressing the monocyte marker …
Comprehensive Phenotyping of Human Dendritic Cells and …
Nov 16, 2020 · In humans, two main subsets of DCs occur within circulating HLA-DR + cells and can be distinguished by their expression of CD11c and CD123 (IL-3Ra), namely plasmacytoid …
Characterization of human blood dendritic cell subsets
Dec 15, 2002 · The CD11c + CD1b/c + subset appears the most activated phenotypically and functionally but whether it is derived from a CD14 + precursor as previously suggested 15 18 …
Subsets of CD1c+ DCs: Dendritic Cell Versus Monocyte Lineage
Sep 30, 2020 · When using CD1c to define DC2s, a CD14 + and a CD14 - subset can be detected. The CD14 + subset shares features with monocytes, and this includes substantially …
Human intestinal pro-inflammatory CD11c - Nature
May 9, 2018 · Monocyte-like cells can be identified as CD11c high CCR2 + CX3CR1 + cells, a phenotype also shared by circulating CD14 + monocytes. On the contrary, their Mϕ-like tissue …
Myeloid blood CD11c - American Society of Hematology
Oct 15, 2002 · An alternative to manufacturing in vitro–derived Mo-DCs is to make use of the preformed, in vivo–generated, myeloid blood CD11c + DCs. Myeloid blood CD11c + DCs are …