CD11c is an integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 …

cDCs can be distinguished from other mononuclear phagocytes by their branched “dendritic” morphology and high surface expression of cDC signature genes, including CD11c and MHC …

The leukocyte integrin CD11c is a myeloid marker expressed on most DCs (Table 1). CD11c + DCs can be further subdivided by their expression of CD8α, the alpha chain of the T-cell co …

Jan 9, 2025 · CD11c dendritic cells encompass a variety of subtypes, each with distinct origins, phenotypes, and roles in the immune system. These subtypes contribute to a nuanced …

CD11c + T-bet + atypical B cells (ABCs) have been identified in the context of vaccination, acute and chronic infections and autoimmune disease. However, the origins and functions of ABCs …

It can be employed to determine the subsets of dendritic cells (DC) in the immune system (see CD11c expression in human and murine immune system), but CD11c may be more than a …

CD11c plays a crucial role in cellular adherence, migration, and phagocytosis. Furthermore, it has been linked to inflammation and immune responses in autoimmune diseases such as …

Jun 26, 2018 · CD11c, also known as integrin alpha X, is the most widely used defining marker for dendritic cells (DCs). CD11c can bind complement iC3b and mediate phagocytosis in vitro, for …

Dec 9, 2020 · This study shows that CD11c, a well-known dendritic cell marker, is expressed on HSPCs and serves as their functional regulator. CD11c deficiency leads to the loss of HSPCs …

Feb 6, 2024 · CD11c is widely known as a cell surface marker for dendritic cells, but we recently showed that it regulates neutrophil and T cell functions. Because we found that CD11c …