Complement receptor type 2 (CR2), also known as complement C3d receptor, Epstein–Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein that in humans is encoded by the …

Jan 21, 2010 · Here, we have identified 2 subsets of human transitional B cells based on the differential expression of CD21. CD21 hi transitional cells displayed higher expression of …

Here, we show that CD21 –/low cells represent approximately 5% of B cells in peripheral blood from adults but are barely detectable in cord blood, after excluding transitional B cells.

CD21-/low memory B cells are expanded with age in healthy individuals and in patients with viral infections and autoimmune conditions and are associated with pathogen-specific antibodies as …

CRISPR-Cas9 deletion of CD21 on the Jurkat T-cell line confirmed that CD21 is required for EBV infection. This study has broad implications, as we have defined a function for CD21 on …

Jul 1, 2001 · The CD19/CD21 complex is an essential B cell coreceptor that functions synergistically to enhance signaling through the B cell Ag receptor in response to T cell …

Know comprehensive CD21 protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction.

CD21 (complement receptor 2 / CR2) is 145-kDa type I transmembrane glycoprotein. It belongs to a family of complement proteins, known as regulators of complement activation. The human …

CD21 is a 145 kDa transmembrane protein that contains 15 tandem SCR/SUSHI repeats. CD21 is primarily expressed on B cells, follicular dendritic cells, and T cells. It binds the complement …

In this review, we will discuss one of these subsets, a subset that is expanded in conditions characterized by chronic immune stimulation. This B cell subset lacks, or expresses low, …