Choose Thermo Scientific™ Hypersil™ ODS C18 HPLC Columns for a general purpose C18 phase to use in a broad range of applications. Hypersil stationary phases are recognized as an industry standard in HPLC.

Apr 30, 2024 · C8 and C18 both refer to the alkyl chain of a bonded face of a column. They are both used in the high performance liquid chromatography system. The two columns have some similarities, but they are also different in some way.

Apr 27, 2024 · In the world of reverse-phase HPLC, C18 columns are the go-to for their ability to engage weak Van Der Waal’s forces, attracting and retaining hydrophobic compounds effectively. The versatility of C18 columns stems from their various adaptations to different silica gels.

May 7, 2019 · By identifying key properties of compounds to pass through your C18 columns, you can easily select the best C18 with ease. Compatible with both your current and older types of chromatography instruments. Enhanced lot to lot reproducibility irrespective of …

Mar 18, 2024 · C18 refers to a specific type of stationary phase used in HPLC columns. It stands for octadecyl, which indicates a chain of eighteen carbon atoms. This long hydrocarbon chain is the key feature that makes C18 columns so valuable in HPLC. Here’s why C18 is widely used for HPLC columns:

Thermo Scientific C18 columns are available with a range of characteristics to provide exceptional performance. These columns are broadly used in a wide variety of applications including pharmaceuticals, steroids, fatty acids, phthalates, environmental and more.

Nov 1, 2023 · The C18 column is probably the most popular type of column for high-performance liquid chromatography (HPLC). Providing robust performance for analysis of a wide variety of compounds, C18 has been used in pharmaceuticals, materials, food, environmental, manufacturing, and other industries.

Feb 23, 2020 · The main difference between C8 and C18 column in HPLC is that the C8 column contains octyl carbon chain (C8)-bonded silica as the stationary phase, but the C18 column contains octadecyl carbon chain (C18)-bonded silica.

Feb 1, 2024 · C18 columns reign supreme due to their wide applicability, robust nature, and ability to separate diverse analytes. Factors like particle size, pore size, column dimensions, bonded phase, and carbon load significantly impact column performance.

Jan 3, 2025 · Known for their versatility, stability, and high efficiency, C18 columns are the most commonly used stationary phase in HPLC for analyzing organic compounds, pharmaceuticals, and bioactive substances. The C18 column offers several advantages, making it the most widely used stationary phase in HPLC: