Jan 12, 2025 · Biologicals are a class of medicines made from living cells taken from plants, animals or bacteria. These cells are use in creating many types of health care products, including vaccines. This group of medicines also includes products derived from human blood and plasma for the treatment of many life-threatening diseases and for surgical procedures.

Dec 21, 2020 · This fourth edition of the manual builds on the risk assessment framework introduced in the third edition. A thorough, evidence-based and transparent assessment of the risks allows safety measures to be balanced with the actual risk of working with biological agents on a case-by-case basis.

Jul 7, 2023 · Radiation is the emission of energy as electromagnetic waves or moving subatomic particles. Natural radiation comes from many naturally occurring radioactive materials found in soil, water, air and in the body. Every day, people inhale and ingest forms of radiation from air, food and water. Today, the most common artificial sources of human exposure to radiation are …

Good manufacturing practices (GMP) for biological products were first published by WHO in 1992 (1). This current revision reflects subsequent developments that have taken place in science and technology, and in the application of risk-based approaches to GMP (2–14). The content of this document should be considered complementary to the general recommendations set out in …

Jun 10, 2011 · Biological reference standards are used in qualifying or validating test procedures to ensure uniformity in the designation of potency or activity of biological preparations including vaccines.

Oct 4, 2024 · Micronutrients such as iron, vitamin A, zinc and iodine and their impact on deficiency syndromes. Food and water are the major sources of exposure to both chemical and biological hazards. They impose a substantial health risk to consumers and economic burdens on individuals, communities and nations.

Sep 6, 2018 · Biological and toxin weapons are either microorganisms like virus, bacteria or fungi, or toxic substances produced by living organisms that are produced and released deliberately to cause disease and death in humans, animals or plants. Biological agents like anthrax, botulinum toxin and plague can pose a difficult public health challenge causing large numbers of deaths …

A major industrial application of biotechnology is in the development and preparation of biological medicinal products using genetically engineered bacteria, yeast, fungi, cells or even whole animals and plants.

Jun 17, 2022 · Individual psychological and biological factors such as emotional skills, substance use and genetics can make people more vulnerable to mental health problems. Exposure to unfavourable social, economic, geopolitical and environmental circumstances – including poverty, violence, inequality and environmental deprivation – also increases ...

Jun 18, 2014 · The Guidelines are based on experience gained over three decades in this technically demanding field and replace Guidelines for assuring the quality of pharmaceutical and biological products prepared by recombinant DNA technology.