Axin-1 is a protein that in humans is encoded by the AXIN1 gene. [5] This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a …

Mar 30, 2025 · This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein …

Axin is a cytosolic scaffold protein that plays a crucial role in the Wnt signaling pathway by facilitating the activation and inhibition of the pathway. It interacts with various signaling …

One such protein, Axin, represents a major evolutionarily conserved scaffold protein in metazoans that participates in the WNT pathway and other pathways to regulate diverse cellular processes.

Jan 30, 2024 · AXIN1 plays a well-organized and precise role in complex molecular signaling networks by interacting with certain phosphokinases and the proteins that they bind to. …

Here we review the data that show how Axin regulates multiple signaling pathways by serving as a scaffold protein, controlling diverse cellular functions in proliferation, fate determination, and …

Feb 8, 2025 · This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein …

The products of the two mammalian Axin genes (Axin1 and its homologue Axin2) are essential for the degradation of β catenin, a component of Wnt signalling that is frequently dysregulated in …

Here, we examine the role of different Axin domains in the effects on axis formation and β-catenin levels. We find that the regulators of G-protein signaling domain (major APC-binding site) and …

This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with …