Jan 20, 2024 · ATG14 is a core component of autophagic initiation complex class III Phosphatidylinositol 3-kinase complex 1 (PI3KC3-C1), which consists of VPS34, Beclin1, p150 …

Mar 28, 2025 · ATG14 (Autophagy Related 14) is a Protein Coding gene. Diseases associated with ATG14 include Neurodegeneration With Brain Iron Accumulation and Liver Carcinoma In …

Phosphorylation of phosphatidylinositol (PtdIns) by a PtdIns 3-kinase is an essential process in autophagy. Atg14, a specific subunit of one of the PtdIns 3-kinase complexes, targets the …

Feb 9, 2015 · The essential autophagy mediator ATG14 promotes vesicle fusion by forming homo-oligomers, which bind to a component of the SNARE membrane fusion complex and …

Atg14, a specific subunit of one of the PtdIns 3-kinase complexes, targets the complex to the probable site of autophagosome formation, thereby, sorting the complex to function specifically …

Nov 1, 2023 · Autophagy-related 14 (ATG14) is a key regulator of autophagy. ATG14 is also localized to lipid droplet; however, the function of ATG14 on lipid droplet remains unclear. In …

Jan 20, 2024 · Here, we identify that ATG14, the core unit of the PI3KC3-C1 complex, also targets LD and acts as an autophagic receptor that facilitates LD degradation. A negative regulator, …

Feb 8, 2025 · Atg14 is critical in controlling an autophagy-dependent phosphorylation of beclin-1. We map novel phosphorylation sites to serines 90 and 93 and demonstrate that …

Apr 23, 2015 · Here we report that ATG14 (also known as beclin-1-associated autophagy-related key regulator (Barkor) or ATG14L), an essential autophagy-specific regulator of the class III …

Autophagy-related 14 (ATG14) is a key regulator of autophagy. ATG14 is also localized to lipid droplet; however, the function of ATG14 on lipid droplet remains unclear. In this study, we …