ApoC-III raises plasma triglycerides through inhibition of LPL, stimulation of VLDL secretion, and is a novel factor in modulating intestinal triglyceride trafficking. ApoC-III also stimulates …

Purpose of review: Apolipoprotein C-III (ApoC-III) is a widely known player in triglyceride metabolism, and it has been recently recognized as a polyhedric factor which may regulate …

ApoC-III is an important mediator of an atherogenic dyslipidaemia and increased CVD risk. The hepatic APOC3 expression is induced by carbohydrates (glucose and fructose) and saturated …

ApoC-III glycosylation can predict cardiovascular disease risk. Higher abundance of disialylated (apoC-III 2) over monosialylated (apoC-III 1) glycoforms is associated with lower plasma …

Apolipoprotein C-III also known as apo-CIII, and apolipoprotein C3, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is secreted by the liver as well as the small intestine, …

Jun 1, 2017 · Overall, the current study suggests that high apoC-III levels provide incremental discriminatory power in the assessment of CAD risk, particularly in hypertriglyceridemia states.

ApoC-III has a key role in the metabolism of TG-rich lipoproteins. APOC3 -knockout animals have reduced plasma TG levels, whereas the overexpression of the APOC3 gene increases TG …

Jan 23, 2023 · This review summarizes the different functions of ApoC-III and underlines the recent findings related to its multifaceted pathophysiological role. The role of ApoC-III has …

Objective: ApoC-III (apolipoprotein C-III) glycosylation can predict cardiovascular disease risk. Higher abundance of disialylated (apoC-III 2) over monosialylated (apoC-III 1) glycoforms is …

Apolipoprotein C-III (apoC-III) is known to inhibit lipoprotein lipase (LPL) and function as an important regulator of triglyceride metabolism. In addition, apoC-III has also more recently …