AOM/DSS Model of Colitis-Associated Cancer - PMC
Here we outline the application of the Azoxymethane (AOM)/Dextran sodium sulfate (DSS) model of CAC. The AOM/DSS model is a powerful, reproducible, and relatively inexpensive initiation …
AOM/DSS Model of Colitis-Associated Cancer - PubMed
Here we describe the Azoxymethane (AOM)/Dextran Sodium Sulfate (DSS) mouse model of inflammatory colorectal cancer. Keywords: AOM; Colitis-associated cancer; Colon cancer; …
Inducible mouse models of colon cancer for the analysis of ... - Nature
Dec 14, 2020 · In the AOM–DSS model, symptoms are caused by flares of colitis during the cycles of DSS treatment. Intestinal inflammation accompanies changes in body weight and …
The AOM/DSS murine model for the study of colon …
Mar 24, 2011 · Among the chemically induced CRC models, the combination of a single hit of azoxymethane (AOM) with 1 week exposure to the inflammatory agent dextran sodium …
Modeling Colitis-Associated Cancer with Azoxymethane (AOM) …
The combination of DSS with AOM as a model for colitis associated cancer has gained popularity for its reproducibility, potency, low price, and ease of use. Though they have a shared …
Murine models of colorectal cancer: the azoxymethane (AOM…
Furthermore, it was demonstrated that an AOM/DSS model with a low dose of DSS (1%) can be used to reliably induce colorectal carcinogenesis measured as preneoplastic lesions in both …
Here we outline the application of the Azoxymethane (AOM)/Dextran sodium sulfate (DSS) model of CAC. The AOM/DSS model is a powerful, reproducible, and relatively inexpensive initiation …
Molecular mechanisms in colitis-associated colorectal cancer
Oct 26, 2023 · This has been a challenge to model in mice with commonly used azoxymethane/dextran sodium sulfate (AOM/DSS), which couples the mutagenic substance …
Protocol for colitis-associated colorectal cancer murine model …
Mar 17, 2023 · Inflammatory bowel diseases (IBDs) contribute to the tumorigenesis of colorectal cancer (CRC). Here, we describe a step-by-step protocol for the construction of colitis …
Transdifferentiation of tumor infiltrating innate lymphoid cells …
May 4, 2020 · In order to explore dynamic regulation of tumor infiltrating ILCs during CRC progression, we used azoxymethane/dextran sodium sulfate (AOM/DSS)-induced colitis …