Nov 17, 2020 · Polyamines are critical elements in mammals, but it remains unknown whether adenosyl methionine decarboxylase (AMD1), a rate-limiting enzyme in polyamine synthesis, is required for myeloid...

29108-1-AP targets AMD1 in WB, ELISA applications and shows reactivity with Human samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation. The KRAS-G12D mutation induces metabolic vulnerability in B-cell acute lymphoblastic leukemia. Linkage of methionine addiction, histone lysine hypermethylation, and malignancy. Cited in 16 publications.

Oct 31, 2016 · Here we show that ‘reverse-polarity’ (RP)-ABPP using clickable, nucleophilic hydrazine probes can capture and identify protein-bound electrophiles in cells. Using this approach, we demonstrate that...

Here we show that mechanistic target of rapamycin complex 1 (mTORC1) regulates polyamine dynamics, a metabolic route that is essential for oncogenicity.

Nov 20, 2020 · Polyamines are critical elements in mammals, but it remains unknown whether adenosyl methionine decarboxylase (AMD1), a rate-limiting enzyme in polyamine synthesis, is required for myeloid leukemia. Here, we found that leukemic stem cells (LSCs) were highly differentiated, and leukemia progression w …

western blot with 11052-1-AP (AMD1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. Immunohistochemical analysis of paraffin-embedded human prostate cancer using 11052-1-AP (AMD1 antibody) at dilution of 1:50 (under 10x lens).

AMD1 Human Recombinant produced in E. coli is a single polypeptide chain containing 292 amino acids (68-334) and having a molecular mass of 33.4 kDa. AMD1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Catalog Number GW21944 Formerly listed as GenWay Catalog Number 15-288-21944, S-adenosylmethionine decarboxylase proenzyme Antibody. The product of this gene is an important intermediate enzyme in polyamine biosynthesis.

Rabbit Polyclonal AMD1 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human AMD1 aa 1-250.