10-formyltetrahydrofolate dehydrogenase is an enzyme that in humans is encoded by the ALDH1L1 gene. [5] The protein encoded by this gene catalyzes the conversion of 10 …

Mar 30, 2025 · ALDH1L1 (Aldehyde Dehydrogenase 1 Family Member L1) is a Protein Coding gene. Diseases associated with ALDH1L1 include Focal Dermal Hypoplasia and Intellectual …

In this study, we evaluated the potential of ALDH1L1 as a therapeutic target by deleting the Aldh1l1 gene in Kras LA2 mice, a model of spontaneous non-small cell lung cancer (NSCLC). …

Feb 8, 2025 · One-carbon metabolizing enzyme ALDH1L1 influences mitochondrial metabolism through 5-aminoimidazole-4-carboxamide ribonucleotide accumulation and serine depletion, …

The metabolic enzyme for folate, Aldh1L1, has been shown to be expressed robustly in astrocytes of the brain. It is now well accepted that astrocytes in certain regions of the adult brain also …

ALDH1L1 is a prognostic marker in Kidney renal clear cell carcinoma, Thyroid carcinoma

Feb 8, 2025 · Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke.

Jan 4, 2025 · One-carbon metabolizing enzyme ALDH1L1 influences mitochondrial metabolism through 5-aminoimidazole-4-carboxamide ribonucleotide accumulation and serine depletion, …

The metabolic enzyme for folate, Aldh1L1, has been shown to be expressed robustly in astrocytes of the brain. It is now well accepted that astrocytes in certain regions of the adult brain also …

ALDH1L1 encodes 10-formyltetrahydrofolate dehydrogenase (FTHFD; EC 1.5.1.6), a cytosolic enzyme that catalyzes the NADP (+)-dependent oxidation of 10-formyltetrahydrofolate to …