AGRP neurons are sufficient to orchestrate feeding behavior
Jan 5, 2011 · Two intermingled hypothalamic neuron populations specified by expression of agouti-related peptide (AGRP) or pro-opiomelanocortin (POMC) positively and negatively …
Hunger neurons drive feeding through a sustained, positive ... - eLife
Aug 24, 2016 · Agouti-related protein (AgRP) neurons within the arcuate nucleus (ARC) of the hypothalamus are a molecularly-defined cell type that is particularly important for the control of …
Neurons for hunger and thirst transmit a negative-valence …
Apr 27, 2015 · To investigate whether elevated AGRP neuron activity transmits a negative-valence signal, we performed flavour preference conditioning using ad libitum fed mice …
AgRP neurons trigger long-term potentiation and facilitate food …
It has been recently reported that activation of AgRP neurons, either by food deprivation or by ChR2-mediated optogenetic stimulation, enhances mouse’s learning for spatial cues …
AgRP Neurons Can Increase Food Intake during Conditions of …
To determine whether AgRP neuron stimulation is sufficient to induce feeding during various appetite-suppressing conditions, we unilaterally injected AAV carrying a Cre-dependent ChR2 …
AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin ...
Mar 24, 2016 · We demonstrate that acute activation of AgRP neurons causes insulin resistance through impairment of insulin-stimulated glucose uptake into brown adipose tissue (BAT). …
An excitatory paraventricular nucleus to AgRP neuron circuit that ...
Feb 2, 2014 · Agouti-related peptide (AgRP)-expressing neurons in the arcuate nucleus (ARC) at the base of the hypothalamus are crucial to the control of hunger. They are activated by caloric...
An mPOA-ARC AgRP pathway modulates cold-evoked eating behavior …
Aug 10, 2021 · We find that the hypothalamic orexigenic agouti-related neuropeptide (AgRP) neurons in the arcuate nucleus (ARC) are profoundly activated by cold exposure. The calcium …
Anti-inflammatory effects of hunger are transmitted to the …
Nov 28, 2023 · We find that AgRP neurons projecting to the paraventricular nucleus of the hypothalamus rapidly and robustly reduce inflammation and mediate the majority of hunger’s …
AgRP neuron activity promotes associations between sensory and ...
Dec 1, 2023 · We engineered Agrp-Ires-Cre mice to express channelrhodopsin-2 (ChR2, by crossing with Ai32 mice) or tdTomato (control, by crossing with Ai9 mice) to enable …
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