Feb 1, 2020 · NG2 cells, which comprise a cycling population of glial cells, appear in the early phases of development and are present in the adult central nervous system. When a specific …

May 5, 2016 · NG2 + cells are a unique glial population in that they display many characteristics typically associated with neurons. These include the expression of ‘neuronal’ genes, such as …

NG2 could, therefore, play a role in experimental autoimmune encephalomyelitis (EAE), a disease associated with increased blood–brain barrier (BBB) permeability, inflammatory infiltrates, and …

Nerve/glial antigen 2 (NG2) is a protein marker of NG2 glia and mural cells, and NG2 promoter activity is utilized to target these cells. However, the NG2 promoter cannot target NG2 glia and …

Jul 28, 2024 · Nerve-glial antigen 2 (NG2, UniProtKB - Q6UVK1), also known as chondroitin sulfate proteoglycan 4 (CSPG4), high molecular weight melanoma-associated antigen (HMW …

Our findings suggest that NG2 glial cells maintain neuronal function and survival via the control of neuroimmunological function. Tissue-specific stem/progenitor cell differentiation maintains …

May 1, 2010 · NG2 cells express GABAA receptors and the AMPA subtype of glutamate receptors. They make intimate contact to neurons prior to myelinating axons and also form …

In adult CNS, nerve/glial-antigen 2 (NG2) is expressed by oligodendrocyte progenitor cells (OPCs) and is an early marker of pericyte activation in pathological conditions.

Mar 30, 2016 · Our data suggest that NG2 plays a role in EAE not only at CNS/BBB level, but also at immune response level, impacting on DC activation and thereby their stimulation of reactive …

Sep 16, 2022 · NG2 is a surface type I transmembrane core protein belonging to the family of chondroitin proteoglycans, has a large extracellular domain, a shorter cytoplasmic part, and is …