The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress …

A genetic rearrangement (translocation) involving the ABL1 gene causes a type of cancer of blood-forming cells called chronic myeloid leukemia. This slow-growing cancer leads to an …

Mar 28, 2025 · ABL1 (ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase) is a Protein Coding gene. Diseases associated with ABL1 include Congenital Heart Defects And Skeletal …

Gene ID: 25, updated on 20-Feb-2025. This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, …

The ABL1 gene provides instructions for making a protein involved in many processes in cells throughout the body. The ABL1 protein functions as a kinase, which is an enzyme that …

The Abelson (ABL) family of nonreceptor tyrosine kinases, ABL1 and ABL2, transduces diverse extracellular signals to protein networks that control proliferation, survival, migration, and …

The Abl family of cytoplasmic tyrosine kinases consists of 2 members, Abl and Arg (Abl-related gene), encoded by the ABL1 and ABL2 genes in humans, and has important roles in various …

Apr 7, 2025 · Depression accelerates the development of gastric cancer through reactive oxygen species‑activated ABL1 (Review). Huang T, et al. Oncol Rep, 2016 Nov. PMID 27666407. …

Nov 22, 2020 · Recently, germline missense variants in ABL1 have been found to cause an autosomal dominant developmental syndrome with congenital heart disease, skeletal …

Apr 9, 2025 · BCR::ABL1 in the general population mirrored CML incidence, and advanced and/or blast phase CML was characterized by subsequent genomic evolution. These data highlight …