Mar 12, 2025 · Repatha (evolocumab) is a PCSK9 inhibitor used to lower high cholesterol alongside dietary changes and to reduce the risk of major cardiovascular events in those with cardiovascular disease, such as death from cardiovascular disease, heart attack, stroke, angina requiring hospitalization, or certain types of heart surgery. Includes Repatha side effects, …

May 17, 2024 · Repatha is a brand (trade) name for evolocumab which may be used to treat high cholesterol. Repatha (evolocumab) works by binding to a protein in the liver called proprotein convertase subtilisin kexin 9 (PCSK9) inhibiting its binding to low-density lipoprotein receptors (LDLR) on the surface of liver cells.

Mar 16, 2025 · Evolocumab (brand name Repatha) is a PCSK9 inhibitor used for hypercholesterolemia (high cholesterol) and cardiovascular risk reduction. It is given by injection under the skin (subcutaneously) 1 time a month or every 2 weeks. Includes evolocumab side effects, interactions and indications.

Feb 5, 2025 · Repatha is used to prevent heart attacks, strokes and the need for coronary revascularization in those with existing cardiovascular disease. It is also used to reduce low-density lipoprotein (LDL) or ‘bad’ cholesterol in certain people with hyperlipidemia or hypercholesterolemia.

Jan 6, 2025 · Repatha side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Sep 19, 2024 · Repatha (evolocumab) works by helping the liver reduce levels of "bad" cholesterol (low-density lipoprotein cholesterol) circulating in your blood by inhibiting a protein called PCSK9. Reducing low-density lipoprotein cholesterol in the blood slows the formation of the fatty deposits in the arteries (atherosclerosis) and reduces the risk of ...

Feb 24, 2025 · REPATHA is a clear to opalescent, colorless to pale yellow solution. Do not use if the solution is cloudy, discolored, or contains particles. Administer REPATHA subcutaneously into areas of the abdomen, thigh, or upper arm that are not tender, bruised, red, or indurated.

Repatha (evolocumab) is a monoclonal antibody targeting PCSK9 (proprotein convertase subtilisin/kexin type 9) used for the treatment of familial hypercholesterolemia (heterozygous and homozygous), and to reduce the risk of adverse cardiovascular events in adults with established cardiovascular disease (CVD).

Sep 19, 2024 · Yes, Repatha is effective at reducing low-density lipoprotein cholesterol (LDL-C) levels when taken on its own, without an additional statin. In the 52 weeks clinical trial DESCARTES they compared placebo treatment, with Repatha on its own, Repatha with 10mg/d of atorvastatin, and Repatha with 80mg/d of atorvastatin.

Sep 19, 2024 · If you stop taking Repatha and once all of the Repatha has left the body the LDL-C levels will start to increase once again causing fatty deposits to accumulate in the arteries. In the FOURIER clinical trial for Repatha the median length of time patients were on Repatha was 24.8 months and 5% of the participants were on it for 36 months.