CD5 includes a scavenger receptor cysteine-rich protein domain. T cells express higher levels of CD5 than B cells. CD5 is upregulated on T cells upon strong activation. In the thymus, there is …

Jan 30, 2025 · CD5 is typically expressed in chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL), thereby distinguishing these disorders from other small chronic B cell …

May 25, 2023 · It had been clear, that the antiquated T cell marker CD5 is important for T cell receptor signaling fine tuning and for protection from activation-induced cell death. 2 …

Mar 28, 2025 · CD5 (CD5 Molecule) is a Protein Coding gene. Diseases associated with CD5 include Thymic Carcinoma and Prolymphocytic Leukemia. Among its related pathways are …

CD5 is a molecule involved in signal transduction through tyrosine phosphorylation of intracellular proteins. It plays a role in modulating signaling via antigen-specific receptor complexes in T …

CD5 is a protein normally found on the surface of specific immune cells, particularly certain types of lymphocytes (a kind of white blood cell). CD5 helps these immune cells communicate and …

CD5 is a scavenger-like receptor expressed in association with the antigen-specific receptors on T and B-1a lymphocytes. Recent studies reveal a broader biology for CD5 that includes its role …

CD5 is a negative regulator of B-cell receptor (BCR) signaling that is up-regulated after BCR stimulation and likely contributes to B-cell tolerance in vivo. However, CD5 is constitutively …

CD5 is a well established negative regulator of TCR and BCR signalling. In the last years, great advances have been made in understanding the molecular mechanisms behind this regulatory …

Dec 7, 2018 · Here we focus on CD5, a transmembrane receptor that regulates T cell functions and development but remains poorly characterized at the molecular level. We will review its …