The CD44 antigen is a cell -surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. In humans, the CD44 antigen is encoded by the CD44 gene on chromosome …

Mar 28, 2025 · CD44 (CD44 Molecule (IN Blood Group)) is a Protein Coding gene. Diseases associated with CD44 include Hematologic Cancer and Congenital Dyserythropoietic Anemia. …

Here, we review current data on the structural and functional properties of CD44, the known roles for CD44 in tumorigencity, the regulation of CD44 expression, and the potential for targeting …

In general, CD44 molecules have seven sites available for N-linked and O-linked glycosylation. CD44 has been shown to bind to hyaluronic acid, heparin sulfate, collagen, and fibronectin (all …

CD44 is a prominent activation marker which distinguishes memory and effector T cells from their naïve counterparts. It also plays a role in early T cell signaling events as it is bound to the …

Jan 1, 2003 · CD44 and its associated partner proteins monitor changes in the extracellular matrix that influence cell growth, survival and differentiation.

CD44 is a multifunctional receptor involved in cell-cell and cell-ECM interactions, cell traffic, lymph node homing, presentation of chemokines and growth factors to traveling cells, and …

Mar 7, 2017 · CD44 is a cell surface adhesion receptor that is highly expressed in many cancers and regulates metastasis via recruitment of CD44 to the cell surface. Its interaction with …

Increasing evidence suggests that some CD44 isoforms are promising prognostic biomarkers and therapeutic targets for many cancers. This review summarises current insights on CD44 …

One molecule that appears to be involved in multiple steps of normal immune cell function is now called CD44 and has been known previously as PgP-1, In (Lu)-related p80, Hermes, ECM-III …