Busulfan (Myleran, GlaxoSmithKline, Busulfex IV, Otsuka America Pharmaceutical, Inc.) is a chemotherapy drug in use since 1959. It is a cell cycle non-specific alkylating antineoplastic …

Mar 10, 2024 · As an antineoplastic alkylating agent, busulfan is a crucial medication for treating these conditions, which warrants a review of its indications, mechanisms of action, and …

Busulfan is a chemotherapy medication that treats chronic myelogenous leukemia. This is a bone marrow cancer. It begins in your blood-forming cells and can spread to other areas of your …

Apr 25, 2024 · Busulfan oral (taken by mouth) is used to treat the symptoms of chronic myelogenous leukemia (a type of blood cancer). Busulfan is not a cure for leukemia. Busulfan …

Mar 1, 2025 · Busulfan injection is used in combination with cyclophosphamide as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation for treatment of …

Busulfan is used treat a certain type of chronic myelogenous leukemia (CML; a type of cancer of the white blood cells). Busulfan is in a class of medications called alkylating agents. It works …

Feb 21, 2014 · This page contains brief information about busulfan and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

Nov 2, 2022 · Busulfan is a bifunctional alkylating agent in which two labile methanesulfonate groups are attached to opposite ends of a four-carbon alkyl chain. In aqueous media, busulfan …

Busulfan is used to treat blood cancers. It is used in high doses together with other chemotherapy drugs before a stem cell transplant. It is also used in low doses to treat other types of blood …

Feb 17, 2020 · Busulfan is an alkylating agent which reacts with the N-7 position of guanosine and interferes with DNA replication and transcription of RNA. Busulfan has a more marked …