Aug 23, 2023 · Afatinib (Gilotrif) is a cancer drug used to treat non-small cell lung cancer (NSCLC) that is EGFR (epidermal growth factor receptor)-positive, which means that it is caused by an abnormal EGFR gene or genes.

Afatinib, sold under the brand name Gilotrif among others, is a medication which is used to treat non-small cell lung carcinoma (NSCLC). [2] [3] [4] It belongs to the tyrosine kinase inhibitor family of medications. [5] It is taken by mouth. [5] [1]

Feb 28, 2024 · Afatinib is a tyrosine kinase inhibitor for managing non–small cell lung carcinoma (NSCLC). Afatinib is designed to cause irreversible inhibition of the ErbB family of tyrosine kinases. The FDA has approved afatinib for treating locally advanced or metastatic NSCLC characterized by nonresistant epidermal growth factor receptor (EGFR) mutations.

Co-administration of P-gp inhibitors can increase afatinib exposure. Reduce GILOTRIF by 10 mg per day if not tolerated. Co-administration of chronic P-gp inducers orally can decrease afatinib...

Afatinib is an antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy.

Dec 27, 2006 · Afatinib is used to treat metastatic (cancer that has already spread) non-small cell lung cancer (NSCLC) that has certain types of abnormal epidermal growth factor receptor (EGFR) genes in patients who have not received any treatments for cancer that has already spread to other parts of the body.

Feb 28, 2025 · Gilotrif (afatinib) is commonly used to treat certain types of non-small-cell lung cancer (NSCLC). Gilotrif may also be used for other conditions as determined by your health care...

Afatinib (Giotrif®) is a targeted therapy drug. It is used to treat non-small cell lung cancer (NSCLC) that has spread. Learn more about it.

Afatinib is used to treat certain types of non-small cell lung cancer that has spread to nearby tissues or to other parts of the body. Afatinib is in a class of medications called kinase inhibitors. It works by blocking the action of a certain naturally occurring substance that may be needed to help cancer cells multiply.

Afatinib is a called a cancer growth blocker. It blocks the signals (messages) of particular proteins that tell a cancer to divide and grow. So this can help slow down or stop the cancer growing.