Mar 30, 2025 · MTOR (Mechanistic Target Of Rapamycin Kinase) is a Protein Coding gene. Diseases associated with MTOR include Smith-Kingsmore Syndrome and Focal Cortical …

The mammalian target of rapamycin (mTOR), [5] also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated protein 1 …

The MTOR gene provides instructions for making a protein called mTOR. This protein is found in various cell types throughout the body including brain cells. It interacts with other proteins to …

Mammalian target of rapamycin (mTOR) gene expression in hidradenitis suppurativa (HS). mTOR was increased in lesional (LS) and nonlesional (NLS) skin compared to normal skin (NS) of …

Oct 2, 2023 · Here, we provide the detailed structure of mTOR, its complexes, and the comprehensive role of upstream regulators, as well as downstream effectors of mTOR …

mTOR is a serine/threonine protein kinase in the PI3K-related kinase (PIKK) family that forms the catalytic subunit of two distinct protein complexes, known as mTOR Complex 1 (mTORC1) …

According to the American College of Medical Genetics and Genomics (ACMG) classification, a likely pathogenic variant was identified in heterozygosis in the MTOR gene, c.5663T>G …

Jan 2, 2019 · In this Review, we introduce the landmark discoveries in the mTOR field, starting from the isolation of rapamycin to the molecular characterizations of key components of the …

MTOR gene mutations that cause Smith-Kingsmore syndrome are germline mutations, which means they are present in cells throughout the body. The most common mutation, found in …

Mechanistic target of rapamycin (MTOR) is a gene that encodes a family of phosphatidylinositol kinase-related kinases. Activating MTOR mutations increase the kinase activity of MTOR, …