EGFR CRISPR/Cas9 KO Plasmid (human) consists of a pool of three plasmids, each encoding the Cas9 nuclease and a target-specific 20-nucleotide gRNA designed for maximum knockout …

EGFR KO cell line available to order. KO validated by Next Generation Sequencing. Free of charge wild type control provided.

The role of VSM-EGFR during high-fat diet (HFD)-induced type 2 diabetes was investigated in a mouse model with inducible, VSM-specific EGFR-knockout (KO). Various structural and …

Apr 16, 2024 · To study the function of EGFR in Wnt9a-Fzd9b endocytosis, we generated EGFR KO HEK293 cells using CRISPR-Cas9 editing. We identified a clone with several mutations …

EGFR is a tyrosine kinase receptor that upon ligand-induced activation recruits the GRB2–SOS complex to its cytoplasmic domain either directly or through the adaptor protein SHC. SOS …

Mar 31, 2021 · As the importance of endothelial (EC) EGFR in vivo is unknown, we analyzed the impact of EC-EGFR knockout in a conditional mouse model on vascular and renal function …

Use EGFR KO Cell Lysate-HeLa for functional genomics research and drug discovery study.

This tyrosine kinase phosphorylates a number of intracellular substrates that activates pathways leading to cell growth, DNA synthesis and the expression of oncogenes such as fos and jun. …

Jul 21, 2022 · We induced a loss of function phenotype in the eyes, wings, and somatic follicle cells using four EGFR RNAi lines: HMS05003 and JF02283, which produce short hairpin …

We investigated the role of VSM-EGFR during obesity-induced renovascular dysfunction, as well as EGFR-hyperglycaemia crosstalk. Methods: The role of VSM-EGFR during high-fat diet …